METTL11A antibody (N-Term) (Biotin)

Catalog No. ABIN7160790

Product Details anti-METTL11A Antibody (Biotin)

Target: METTL11A (Methyltransferase Like 11A (METTL11A))

Binding Specificity: AA 1-223, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL11A antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human N-terminal Xaa-Pro-Lys N-methyltransferase 1 protein (1-223AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for METTL11A

Target: METTL11A (Methyltransferase Like 11A (METTL11A))

Alternative Name: NTMT1 (METTL11A Products)

Synonyms: C9orf32 antibody, C11H9orf32 antibody, METTL11A antibody, NTM1A antibody, AD-003 antibody, HOMT1A antibody, NRMT antibody, 2610205E22Rik antibody, AL033331 antibody, AL033332 antibody, Mettl11a antibody, RGD1306582 antibody, mettl11a antibody, zgc:77488 antibody, N-terminal Xaa-Pro-Lys N-methyltransferase 1 antibody, NTMT1 antibody, Ntmt1 antibody, ntmt1 antibody

Background:

Background: Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.

Aliases: AD 003 antibody, Alpha N-terminal protein methyltransferase 1A antibody, C9orf32 antibody, Chromosome 9 open reading frame 32 antibody, Methyltransferase like 11A antibody, Methyltransferase-like protein 11A antibody, Mettl11a antibody, N-terminal RCC1 methyltransferase antibody, NRMT antibody, NTM1A antibody, NTM1A_HUMAN antibody, NTMT1 antibody, X-Pro-Lys N-terminal protein methyltransferase 1A antibody

UniProt: Q9BV86