SETD6 antibody (AA 1-74) (HRP)

Catalog No. ABIN7160773

Product Details anti-SETD6 Antibody (HRP)

Target: SETD6 (SET Domain Containing 6 (SETD6))

Binding Specificity: AA 1-74

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD6 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human N-lysine methyltransferase SETD6 protein (1-74AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SETD6

Target: SETD6 (SET Domain Containing 6 (SETD6))

Alternative Name: SETD6 (SETD6 Products)

Synonyms: 0610039J04Rik antibody, 3110004G14Rik antibody, AI413388 antibody, C76402 antibody, RGD1560538 antibody, wu:fb58f11 antibody, zgc:55627 antibody, SET domain containing 6 antibody, SET domain containing 6 L homeolog antibody, SETD6 antibody, Setd6 antibody, setd6 antibody, setd6.L antibody

Background:

Background: Protein-lysine N-methyltransferase. Monomethylates \'Lys-310\' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (PubMed:21131967). Monomethylates \'Lys-8\' of H2AZ (H2AZK8me1) (PubMed:23324626). Required for the maintenance of embryonic stem cell self-renewal (By similarity).

Aliases: SETD6 antibody, N-lysine methyltransferase SETD6 antibody, EC 2.1.1.- antibody, SET domain-containing protein 6 antibody

UniProt: Q8TBK2