FPR2 antibody (AA 307-351) (Biotin)

Catalog No. ABIN7160755

Product Details anti-FPR2 Antibody (Biotin)

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Binding Specificity: AA 307-351

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human N-formyl peptide receptor 2 protein (307-351AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: FPR2 (FPR2 Products)

Synonyms: ALXR antibody, FMLP-R-II antibody, FMLPX antibody, FPR2A antibody, FPRH1 antibody, FPRH2 antibody, FPRL1 antibody, HM63 antibody, LXA4R antibody, E330010I07Rik antibody, Fpr-rs2 antibody, Fprl1 antibody, ALX antibody, Fpr-rs1 antibody, Fpr-s1 antibody, LXA4-R antibody, Lxa4r antibody, FMLP-R-I antibody, FPR2 antibody, formyl peptide receptor 2 antibody, formyl peptide receptor 3 antibody, N-formyl peptide receptor 2 antibody, FPR2 antibody, Fpr2 antibody, Fpr3 antibody, LOC100444626 antibody

Background:

Background: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Aliases: ALXR antibody, FMLP-R-I antibody, FMLP-R-II antibody, FMLP-related receptor I antibody, FMLPX antibody, Formyl peptide receptor 2 antibody, Formyl peptide receptor related antibody, Formyl peptide receptor-like 1 antibody, FPR2 antibody, FPR2_HUMAN antibody, FPR2A antibody, FPRH1 antibody, FPRH2 antibody, FPRL1 antibody, HM63 antibody, Lipoxin A4 receptor antibody, LXA4 receptor antibody, LXA4R antibody, N-formyl peptide receptor 2 antibody, RFP antibody

UniProt: P25090