FAM174A antibody (AA 1-94)

Catalog No. ABIN7160745

Product Details anti-FAM174A Antibody

Target: FAM174A (Family with Sequence Similarity 174, Member A (FAM174A))

Binding Specificity: AA 1-94

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM174A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human N-alpha-acetyltransferase 60 protein (1-94AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAM174A

Target: FAM174A (Family with Sequence Similarity 174, Member A (FAM174A))

Alternative Name: NAA6 (FAM174A Products)

Synonyms: TMEM157 antibody, UNQ1912 antibody, 2310044D20Rik antibody, Fam174 antibody, Naa6 antibody, Tmem157 antibody, RGD1309973 antibody, family with sequence similarity 174 member A antibody, family with sequence similarity 174, member A antibody, FAM174A antibody, Fam174a antibody

Background:

Background: N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol (PubMed:25732826). Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met (PubMed:21750686, PubMed:25732826, PubMed:27550639, PubMed:27320834). Required for normal chromosomal segregation during anaphase (PubMed:21750686). May also show histone acetyltransferase activity, such results are however unclear in vivo and would require additional experimental evidences (PubMed:21981917).

Aliases: FLJ11693 antibody, FLJ14154 antibody, HAT4 antibody, Histone acetyltransferase type B protein 4 antibody, N acetyltransferase 15 (GCN5 related, putative) antibody, N alpha acetyltransferase 60 antibody, N(alpha) acetyltransferase 60, NatF catalytic subunit antibody, N-acetyltransferase 15 antibody, N-alpha-acetyltransferase 60 antibody, naa60 antibody, NAA60_HUMAN antibody, NAT15 antibody, NatF catalytic subunit antibody

UniProt: Q9H7X0