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NAT8 antibody (AA 64-227) (Biotin)

NAT8 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7160713
  • Target See all NAT8 Antibodies
    NAT8 (N-Acetyltransferase 8 (NAT8))
    Binding Specificity
    • 8
    • 6
    • 6
    • 6
    • 4
    • 1
    AA 64-227
    Reactivity
    • 31
    • 11
    • 2
    Human
    Host
    • 30
    • 1
    Rabbit
    Clonality
    • 30
    • 1
    Polyclonal
    Conjugate
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAT8 antibody is conjugated to Biotin
    Application
    • 19
    • 19
    • 17
    • 2
    • 2
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human N-acetyltransferase 8 protein (64-227AA)
    Isotype
    IgG
    Top Product
    Discover our top product NAT8 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NAT8 (N-Acetyltransferase 8 (NAT8))
    Alternative Name
    NAT8 (NAT8 Products)
    Synonyms
    Cml4 antibody, ATase2 antibody, CML1 antibody, GLA antibody, Hcml1 antibody, TSC501 antibody, TSC510 antibody, 0610037O16Rik antibody, N-acetyltransferase 8 antibody, N-acetyltransferase 8 (putative) antibody, N-acetyltransferase 8 (GCN5-related) antibody, Nat8 antibody, NAT8 antibody
    Background

    Background: Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids (PubMed:20392701). This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).

    Aliases: acetyltransferase 2 antibody, ATase2 antibody, Camello, Xenopus, homolog of, 1 antibody, Camello-like protein 1 antibody, CML1 antibody, cysteinyl-conjugate N-acetyltransferase antibody, GLA antibody, Hcml1 antibody, kidney- and liver-specific gene product antibody, N-acetyltransferase 8 (camello like) antibody, N-acetyltransferase 8 (GCN5-related, putative) antibody, N-acetyltransferase 8 antibody, NAT8 antibody, NAT8_HUMAN antibody, Probable N-acetyltransferase 8 antibody, TSC501 antibody, TSC510 antibody

    UniProt
    Q9UHE5
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