NAT8 antibody (AA 64-227) (Biotin)
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- Target See all NAT8 Antibodies
- NAT8 (N-Acetyltransferase 8 (NAT8))
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Binding Specificity
- AA 64-227
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NAT8 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human N-acetyltransferase 8 protein (64-227AA)
- Isotype
- IgG
- Top Product
- Discover our top product NAT8 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- NAT8 (N-Acetyltransferase 8 (NAT8))
- Alternative Name
- NAT8 (NAT8 Products)
- Synonyms
- Cml4 antibody, ATase2 antibody, CML1 antibody, GLA antibody, Hcml1 antibody, TSC501 antibody, TSC510 antibody, 0610037O16Rik antibody, N-acetyltransferase 8 antibody, N-acetyltransferase 8 (putative) antibody, N-acetyltransferase 8 (GCN5-related) antibody, Nat8 antibody, NAT8 antibody
- Background
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Background: Acetylates the free alpha-amino group of cysteine S-conjugates to form mercapturic acids (PubMed:20392701). This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1 (PubMed:24556617). May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (PubMed:19011241).
Aliases: acetyltransferase 2 antibody, ATase2 antibody, Camello, Xenopus, homolog of, 1 antibody, Camello-like protein 1 antibody, CML1 antibody, cysteinyl-conjugate N-acetyltransferase antibody, GLA antibody, Hcml1 antibody, kidney- and liver-specific gene product antibody, N-acetyltransferase 8 (camello like) antibody, N-acetyltransferase 8 (GCN5-related, putative) antibody, N-acetyltransferase 8 antibody, NAT8 antibody, NAT8_HUMAN antibody, Probable N-acetyltransferase 8 antibody, TSC501 antibody, TSC510 antibody
- UniProt
- Q9UHE5
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