NPL antibody (AA 17-77) (Biotin)

Catalog No. ABIN7160708

Product Details anti-NPL Antibody (Biotin)

Target: NPL (N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) (NPL))

Binding Specificity: AA 17-77

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPL antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human N-acetylneuraminate lyase protein (17-77AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NPL

Target: NPL (N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) (NPL))

Alternative Name: NPL (NPL Products)

Background:

Background: Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (By similarity).

Aliases: 0610033B02Rik antibody, C112 antibody, C1orf13 antibody, Dihydrodipicolinate synthase antibody, Dihydrodipicolinate synthetase homolog 1 antibody, MGC149582 antibody, MGC61869 antibody, N-acetylneuraminate lyase antibody, N-acetylneuraminate pyruvate-lyase antibody, N-acetylneuraminic acid aldolase antibody, NAL antibody, NALase antibody, NPL antibody, NPL_HUMAN antibody, NPL1 antibody, RP11-249O6.1 antibody, Sialate lyase antibody, Sialate-pyruvate lyase antibody, Sialic acid aldolase antibody, Sialic acid lyase antibody

UniProt: Q9BXD5