MTM1 antibody (AA 484-603)
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- Target See all MTM1 Antibodies
- MTM1 (Myotubularin 1 (MTM1))
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Binding Specificity
- AA 484-603
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MTM1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Myotubularin protein (484-603AA)
- Isotype
- IgG
- Top Product
- Discover our top product MTM1 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MTM1 (Myotubularin 1 (MTM1))
- Alternative Name
- MTM1 (MTM1 Products)
- Synonyms
- CNM antibody, MTMX antibody, XLMTM antibody, wu:fb19c01 antibody, zgc:123266 antibody, myotubularin 1 antibody, myotubularin 1 S homeolog antibody, MTM1 antibody, mtm1 antibody, mtm1.S antibody, Mtm1 antibody
- Background
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Background: Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
Aliases: AF073996 antibody, CG2 antibody, CNM antibody, KIAA4176 antibody, mKIAA4176 antibody, Mtm antibody, Mtm1 antibody, MTM1_HUMAN antibody, MTMX antibody, Myotubular myopathy 1 antibody, Myotubularin antibody, XLMTM antibody
- UniProt
- Q13496
- Pathways
- Inositol Metabolic Process, Skeletal Muscle Fiber Development
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