MPZL1 antibody (AA 195-258)

Catalog No. ABIN7160421

Product Details anti-MPZL1 Antibody

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Binding Specificity: AA 195-258

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZL1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Myelin protein zero-like protein 1 protein (195-258AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MPZL1

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Alternative Name: MPZL1 (MPZL1 Products)

Synonyms: MPZL1 antibody, MPZL1b antibody, PZR antibody, PZR1b antibody, PZRa antibody, PZRb antibody, 1110007A10Rik antibody, myelin protein zero like 1 antibody, myelin protein zero-like 1 antibody, MPZL1 antibody, Mpzl1 antibody

Background:

Background: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Aliases: MPZL1 antibody, PZR antibody, UNQ849/PRO1787 antibody, Myelin protein zero-like protein 1 antibody, Protein zero-related antibody

UniProt: O95297