MBNL3 antibody (AA 116-211)

Catalog No. ABIN7160361

Product Details anti-MBNL3 Antibody

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Binding Specificity: AA 116-211

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBNL3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Muscleblind-like protein 3 protein (116-211AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MBNL3

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Alternative Name: MBNL3 (MBNL3 Products)

Synonyms: A530038J18Rik antibody, AI661274 antibody, CHCR antibody, E430034C16Rik antibody, MBLX antibody, MBLX39 antibody, MBXL antibody, mbxl antibody, RGD1565834 antibody, muscleblind like splicing regulator 3 antibody, muscleblind like splicing factor 3 antibody, Muscleblind-like protein 3-like antibody, muscleblind-like splicing regulator 3 antibody, MBNL3 antibody, Mbnl3 antibody, mbnl3 antibody

Background:

Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology (DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

Aliases: A530038J18Rik antibody, AI661274 antibody, CHCR antibody, Cys3His CCG1 required protein antibody, Cys3His CCG1-required protein antibody, E430034C16Rik antibody, MBLX antibody, MBLX39 antibody, MBNL 3 antibody, Mbnl3 antibody, MBNL3_HUMAN antibody, MBXL antibody, Muscleblind like 3 antibody, Muscleblind like protein 3 antibody, Muscleblind like splicing regulator 3 antibody, Muscleblind like X linked protein antibody, Muscleblind-like protein 3 antibody, Muscleblind-like X-linked protein antibody, OTTMUSP00000019072 antibody, OTTMUSP00000019073 antibody, OTTMUSP00000019074 antibody, Protein HCHCR antibody, RP23-98P13.1 antibody

UniProt: Q9NUK0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development