FAT Atypical Cadherin 2 (FAT2) (AA 123-314) antibody
-
- Target See all FAT Atypical Cadherin 2 (FAT2) Antibodies
- FAT Atypical Cadherin 2 (FAT2)
- Binding Specificity
- AA 123-314
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Multiple epidermal growth factor-like domains protein 10 protein (123-314AA)
- Isotype
- IgG
-
anti-FAT Atypical Cadherin 2 (FAT2) antibody
FAT2 Reactivity: Human IF, FACS, IHC, StM Host: Mouse Monoclonal 8C5 unconjugated
-
- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- FAT Atypical Cadherin 2 (FAT2)
- Alternative Name
- MEGF1 (FAT2 Products)
- Synonyms
- EMI2 antibody, Fath2 antibody, Gm523 antibody, mKIAA0811 antibody, CDHF8 antibody, CDHR9 antibody, HFAT2 antibody, MEGF1 antibody, FAT atypical cadherin 2 antibody, Fat2 antibody, FAT2 antibody
- Background
-
Background: Membrane receptor involved in phagocytosis by macrophages of apoptotic cells. Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides. May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. May play role in cell adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation problably through regulation of the notch signaling pathway.
Aliases: MEGF10 antibody, KIAA1780Multiple epidermal growth factor-like domains protein 10 antibody, Multiple EGF-like domains protein 10 antibody
- UniProt
- Q96KG7
-
