MADCAM1 antibody (AA 19-317) (Biotin)

Catalog No. ABIN7160299

Product Details anti-MADCAM1 Antibody (Biotin)

Target: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Binding Specificity: AA 19-317

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MADCAM1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mucosal addressin cell adhesion molecule 1 protein (19-317AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MADCAM1

Target: MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))

Alternative Name: MADCAM1 (MADCAM1 Products)

Synonyms: MACAM1 antibody, AV211525 antibody, mucosal vascular addressin cell adhesion molecule 1 antibody, MADCAM1 antibody, Madcam1 antibody

Background:

Background: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Aliases: Addressin mucosal antibody, hMAdCAM 1 antibody, hMAdCAM-1 antibody, MACAM1 antibody, MADCA_HUMAN antibody, MAdCAM 1 antibody, MAdCAM-1 antibody, Madcam1 antibody, Mucosal addressin cell adhesion molecule 1 antibody, Mucosal vascular addressin cell adhesion molecule 1 antibody

UniProt: Q13477