MALT1 antibody (AA 125-450)

Catalog No. ABIN7160297

Product Details anti-MALT1 Antibody

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Binding Specificity: AA 125-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MALT1 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1 protein (125-450AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MALT1

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Alternative Name: MALT1 (MALT1 Products)

Synonyms: malt1 antibody, MALT1 antibody, mlt antibody, mlt1 antibody, MLT antibody, MLT1 antibody, A630046N12 antibody, D430033E09Rik antibody, MALT paracaspase 2 antibody, MALT1 paracaspase antibody, MALT1 paracaspase S homeolog antibody, paracaspase 3 antibody, malt2 antibody, MALT1 antibody, malt1.S antibody, Malt1 antibody, PCASP3 antibody

Background:

Background: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Aliases: Caspase like protein antibody, DKFZp434L132 antibody, IMD12 antibody, MALT 1 antibody, MALT associated translocation antibody, MALT lymphoma associated translocation antibody, MALT lymphoma-associated translocation antibody, Malt1 antibody, MALT1 paracaspase antibody, MALT1_HUMAN antibody, MLT 1 antibody, MLT antibody, MLT1 antibody, Mucosa associated lymphoid tissue lymphoma translocation gene 1 antibody, Mucosa associated lymphoid tissue lymphoma translocation protein 1 antibody, Mucosa-associated lymphoid tissue lymphoma translocation protein 1 antibody, Paracaspase antibody, Paracaspase-1 antibody, PCASP1 antibody

UniProt: Q9UDY8

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins