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MAD2L2 antibody (AA 1-211)

MAD2L2 Reactivity: Human ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7160094
  • Target See all MAD2L2 Antibodies
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    Binding Specificity
    • 15
    • 8
    • 4
    • 2
    • 1
    • 1
    AA 1-211
    Reactivity
    • 40
    • 13
    • 11
    Human
    Host
    • 40
    • 2
    Rabbit
    Clonality
    • 32
    • 10
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAD2L2 antibody is un-conjugated
    Application
    • 31
    • 14
    • 13
    • 13
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Mitotic spindle assembly checkpoint protein MAD2B protein (1-211AA)
    Isotype
    IgG
    Top Product
    Discover our top product MAD2L2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MAD2L2 (MAD2 Mitotic Arrest Deficient-Like 2 (MAD2L2))
    Alternative Name
    MAD2L2 (MAD2L2 Products)
    Synonyms
    mad2b antibody, 2310033C13Rik antibody, MAD2B antibody, REV7 antibody, mad2B antibody, mad2l2-A antibody, xMAD2L2 antibody, POLZ2 antibody, mad2l2 antibody, zgc:110299 antibody, mitotic arrest deficient 2 like 2 antibody, MAD2 mitotic arrest deficient-like 2 antibody, mitotic arrest deficient 2 like 2 S homeolog antibody, MAD2 mitotic arrest deficient-like 2 (yeast) antibody, si:dkey-23c22.2 antibody, mad2l2 antibody, MAD2L2 antibody, Mad2l2 antibody, mad2l2.S antibody, si:dkey-23c22.2 antibody
    Background

    Background: Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.

    Aliases: Homolog of REV7 S cerevisiae antibody, hREV7 antibody, MAD2 (mitotic arrest deficient yeast, homolog) like 2 antibody, MAD2 homolog antibody, MAD2 like 2 antibody, MAD2 mitotic arrest deficient like 2 antibody, MAD2-like protein 2 antibody, MAD2B antibody, Mad2l2 antibody, MD2L2_HUMAN antibody, Mitotic Arrest Deficient 2 L2 antibody, Mitotic arrest deficient 2-like protein 2 antibody, Mitotic arrest deficient homolog like 2 antibody, Mitotic arrest deficient like 2 (yeast) antibody, Mitotic arrest deficient yeast homolog antibody, Mitotic spindle assembly checkpoint protein MAD2B antibody, Polymerase (DNA directed) zeta 2 accessory subunit antibody, POLZ2 antibody, REV 7 antibody, REV7 antibody, REV7 homolog antibody, Weakly similar to Mitotic MAD2 protein (S cerevisiae) antibody

    UniProt
    Q9UI95
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