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BUB1B antibody (AA 230-394)

BUB1B Reactivity: Human IHC, ELISA, IF, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7160080
  • Target See all BUB1B Antibodies
    BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
    Binding Specificity
    • 15
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 230-394
    Reactivity
    • 75
    • 38
    • 11
    • 3
    • 1
    Human
    Host
    • 54
    • 21
    • 5
    Rabbit
    Clonality
    • 58
    • 22
    Polyclonal
    Conjugate
    • 50
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BUB1B antibody is un-conjugated
    Application
    • 65
    • 25
    • 22
    • 22
    • 14
    • 13
    • 13
    • 7
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Mitotic checkpoint serine/threonine-protein kinase BUB1 beta protein (230-394AA)
    Isotype
    IgG
    Top Product
    Discover our top product BUB1B Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500, IP:1:200-1:2000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
    Alternative Name
    BUB1B (BUB1B Products)
    Synonyms
    BUB1beta antibody, BUBR1 antibody, Bub1A antibody, MAD3L antibody, MVA1 antibody, SSK1 antibody, hBUBR1 antibody, AU045529 antibody, bub1b antibody, BUB1 antibody, BUB1-like antibody, BubR1 antibody, BubRI antibody, CG14030 antibody, CG14030/Bub1 antibody, Dmel\\CG14030 antibody, bub1 antibody, BUB1 mitotic checkpoint serine/threonine kinase B antibody, BUB1B, mitotic checkpoint serine/threonine kinase antibody, BUB1B, mitotic checkpoint serine/threonine kinase L homeolog antibody, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta antibody, Bub1 kinase antibody, BUB1B antibody, Bub1b antibody, bub1b.L antibody, bub1b antibody, Bub1 antibody
    Background

    Background: Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively regulates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression.

    Aliases: Beta homolg of S. cerevisiae BUB 1 antibody, Beta homolg of S. cerevisiae budding uninhibited by benzimidazoles antibody, BUB 1B antibody, BUB1 budding uninhibited by benzimidazoles 1 homolog beta antibody, Bub1A antibody, BUB1B antibody, BUB1B_HUMAN antibody, BUB1beta antibody, BUBR1 antibody, Budding Uninhibited by Benzimidazoles 1 beta antibody, Budding uninhibited by benzimidazoles 1 homolog beta (yeast) antibody, hBUBR1 antibody, MAD3/BUB1 related protein kinase antibody, MAD3/BUB1-related protein kinase antibody, MAD3L antibody, Mitotic checkpoint gene BUB1B antibody, Mitotic checkpoint kinase MAD3L antibody, Mitotic checkpoint serine/threonine protein kinase BUB1 beta antibody, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta antibody, MVA1 antibody, OTTHUMP00000160319 antibody, Protein SSK1 antibody, SSK 1 antibody, SSK1 antibody

    UniProt
    O60566
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