BUB3 antibody (AA 6-217)

Catalog No. ABIN7160076

Product Details anti-BUB3 Antibody

Target: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Binding Specificity: AA 6-217

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BUB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mitotic checkpoint protein BUB3 protein (6-217AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BUB3

Target: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Alternative Name: BUB3 (BUB3 Products)

Synonyms: BUB3L antibody, hBUB3 antibody, Aa2-050 antibody, xbub3 antibody, AU019800 antibody, AU021329 antibody, AU043350 antibody, AW146323 antibody, C78067 antibody, BUB3, mitotic checkpoint protein antibody, BUB3 mitotic checkpoint protein antibody, BUB3 mitotic checkpoint protein L homeolog antibody, BUB3 antibody, Bub3 antibody, bub3.L antibody

Background:

Background: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.

Aliases: Aa2-050 antibody, AU019800 antibody, AU021329 antibody, AU043350 antibody, AW146323 antibody, BUB 3 antibody, BUB 3L antibody, BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog antibody, bub3 antibody, BUB3 budding uninhibited by benzimidazoles 3 homolog antibody, BUB3 mitotic checkpoint protein antibody, BUB3_HUMAN antibody, BUB3L antibody, Budding uninhibited by benomyl antibody, Budding uninhibited by benzimidazoles 3 antibody, Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) antibody, Budding uninhibited by benzimidazoles 3 homolog (yeast) antibody, Budding uninhibited by benzimidazoles 3 homolog antibody, Budding uninhibited by benzimidazoles 3, S. cerevisiae, homolog of antibody, C78067 antibody, hBUB3 antibody, Mitotic checkpoint component antibody, Mitotic checkpoint protein bub3 antibody, OTTHUMP00000020679 antibody, OTTHUMP00000020680 antibody, WD repeat type I transmembrane protein A72.5 antibody

UniProt: O43684

Pathways: Maintenance of Protein Location