MAP3K13 antibody (AA 506-835) (HRP)

Catalog No. ABIN7160028

Product Details anti-MAP3K13 Antibody (HRP)

Target: MAP3K13 (Mitogen-Activated Protein Kinase Kinase Kinase 13 (MAP3K13))

Binding Specificity: AA 506-835

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K13 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mitogen-activated protein kinase kinase kinase 13 protein (506-835AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAP3K13

Target: MAP3K13 (Mitogen-Activated Protein Kinase Kinase Kinase 13 (MAP3K13))

Alternative Name: MAP3K13 (MAP3K13 Products)

Synonyms: LZK antibody, MEKK13 antibody, MLK antibody, C130026N12Rik antibody, lzk antibody, map3k13 antibody, map3k13a antibody, mekk13 antibody, map3k13-a antibody, map3k13-b antibody, map3k13b antibody, mitogen-activated protein kinase kinase kinase 13 antibody, mitogen-activated protein kinase kinase kinase 13 L homeolog antibody, mitogen-activated protein kinase kinase kinase 13 S homeolog antibody, MAP3K13 antibody, Map3k13 antibody, map3k13.L antibody, map3k13 antibody, map3k13.S antibody

Background:

Background: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Aliases: EC 2.7.11.25 antibody, Leucine zipper bearing kinase antibody, Leucine zipper-bearing kinase antibody, LZK antibody, M3K13_HUMAN antibody, MAP3K13 antibody, MEKK13 antibody, MGC133196 antibody, Mitogen activated protein kinase kinase kinase 13 antibody, Mitogen-activated protein kinase kinase kinase 13 antibody, Mixed lineage kinase antibody, MLK antibody, OTTHUMP00000210397 antibody

UniProt: O43283

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2