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RPUSD4 antibody (AA 41-240) (Biotin)

RPUSD4 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7159948
  • Target See all RPUSD4 Antibodies
    RPUSD4 (RNA Pseudouridylate Synthase Domain Containing 4 (RPUSD4))
    Binding Specificity
    • 4
    • 1
    AA 41-240
    Reactivity
    • 7
    • 2
    • 2
    Human
    Host
    • 7
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 4
    • 2
    • 1
    This RPUSD4 antibody is conjugated to Biotin
    Application
    • 4
    • 3
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Mitochondrial RNA pseudouridine synthase RPUSD4 protein (41-240AA)
    Isotype
    IgG
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    Discover our top product RPUSD4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    RPUSD4 (RNA Pseudouridylate Synthase Domain Containing 4 (RPUSD4))
    Alternative Name
    RPUSD4 (RPUSD4 Products)
    Synonyms
    2410001E19Rik antibody, RGD1311268 antibody, RNA pseudouridylate synthase domain containing 4 antibody, RPUSD4 antibody, Rpusd4 antibody
    Background

    Background: Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome (PubMed:27974379). Acts on position 39 in mitochondrial tRNA(Phe) (PubMed:28082677). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation (PubMed:27667664).

    Aliases: RNA pseudouridylate synthase domain-containing protein 4 antibody, rpusd4 antibody, RUSD4_HUMAN antibody

    UniProt
    Q96CM3
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