TIMM8A/DDP antibody (AA 1-97)

Catalog No. ABIN7159907

Product Details anti-TIMM8A/DDP Antibody

Target: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Binding Specificity: AA 1-97

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM8A/DDP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Mitochondrial import inner membrane translocase subunit Tim8 A protein (1-97AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TIMM8A/DDP

Target: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Alternative Name: TIMM8A (TIMM8A Products)

Background:

Background: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Aliases: DDP 1 antibody, DDP antibody, DDP1 antibody, Deafness dystonia protein 1 antibody, Deafness/dystonia peptide antibody, DFN 1 antibody, DFN1 antibody, MGC12262 antibody, Mitochondrial import inner membrane translocase subunit Tim8 A antibody, MTS antibody, TIM 8A antibody, TIM8 antibody, TIM8A antibody, TIM8A_HUMAN antibody, TIMM 8A antibody, timm8a antibody, Translocase of inner mitochondrial membrane 8 homolog A antibody, X linked deafness dystonia protein antibody, X-linked deafness dystonia protein antibody

UniProt: O60220