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C20orf72 antibody (AA 81-260) (FITC)

MGME1 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7159876
  • Target See all C20orf72 (MGME1) products
    C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
    Binding Specificity
    • 15
    • 4
    • 1
    AA 81-260
    Reactivity
    • 28
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C20orf72 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Mitochondrial genome maintenance exonuclease 1 protein (81-260AA)
    Isotype
    IgG
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
    Alternative Name
    MGME1 (MGME1 Products)
    Synonyms
    C20orf72 antibody, DDK1 antibody, MTDPS11 antibody, bA504H3.4 antibody, mitochondrial genome maintenance exonuclease 1 antibody, MGME1 antibody
    Background

    Background: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5\'-3\' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.

    Aliases: MGME1 antibody, C20orf72 antibody, DDK1Mitochondrial genome maintenance exonuclease 1 antibody, EC 3.1.-.- antibody

    UniProt
    Q9BQP7
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