Fission 1 antibody (AA 1-122)

Catalog No. ABIN7159861

Product Details anti-Fission 1 Antibody

Target: Fission 1 (FIS1)

Binding Specificity: AA 1-122

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mitochondrial fission 1 protein (1-122AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: FIS1 (FIS1 Products)

Synonyms: TTC11 antibody, 2010003O14Rik antibody, Ttc11 antibody, fission, mitochondrial 1 antibody, FIS1 antibody, Fis1 antibody

Background:

Background: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Aliases: 2010003O14Rik antibody, CGI 135 antibody, CGI135 antibody, FIS 1 antibody, FIS1 antibody, Fis1 homolog antibody, FIS1, S. cerevisiae, homolog of antibody, FIS1_HUMAN antibody, Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) antibody, Fission 1 (mitochondrial outer membrane) homolog (yeast) antibody, Fission 1 (mitochondrial outer membrane) homolog antibody, Fission 1 homolog antibody, H NH0132A01.6 antibody, hFis 1 antibody, hFis1 antibody, Mitochondrial fission 1 protein antibody, mitochondrial fission molecule antibody, Tetratricopeptide repeat domain 11 antibody, Tetratricopeptide repeat protein 11 antibody, TPR repeat protein 11 antibody, TTC 11 antibody, TTC11 antibody

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity