MCMBP antibody (AA 1-240)

Catalog No. ABIN7159821

Product Details anti-MCMBP Antibody

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Binding Specificity: AA 1-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCMBP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Mini-chromosome maintenance complex-binding protein (1-240AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCMBP

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Alternative Name: MCMBP (MCMBP Products)

Background:

Background: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP, probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion.

Aliases: MCMBP antibody, C10orf119 antibody, Mini-chromosome maintenance complex-binding protein antibody, MCM-BP antibody, MCM-binding protein antibody

UniProt: Q9BTE3

Pathways: Chromatin Binding