MAP1LC3B2 antibody (AA 1-47)

Catalog No. ABIN7159774

Product Details anti-MAP1LC3B2 Antibody

Target: MAP1LC3B2 (Microtubule-Associated Protein 1 Light Chain 3 beta 2 (MAP1LC3B2))

Binding Specificity: AA 1-47

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1LC3B2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Microtubule-associated proteins 1A/1B light chain 3 beta 2 protein (1-47AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAP1LC3B2

Target: MAP1LC3B2 (Microtubule-Associated Protein 1 Light Chain 3 beta 2 (MAP1LC3B2))

Alternative Name: MAP1LC3B2 (MAP1LC3B2 Products)

Synonyms: ATG8G antibody, microtubule associated protein 1 light chain 3 beta 2 antibody, MAP1LC3B2 antibody

Background:

Background: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).

Aliases: ATG8G antibody, MAP1LC3B2 antibody, Microtubule associated protein 1 light chain 3 beta 2 antibody, Microtubule associated proteins 1A/1B light chain 3B like protein antibody, Microtubule-associated proteins 1A/1B light chain 3 beta 2 antibody, Microtubule-associated proteins 1A/1B light chain 3B-like antibody, MP3B2_HUMAN antibody

UniProt: A6NCE7