APOO antibody (AA 26-198) (Biotin)

Catalog No. ABIN7159689

Product Details anti-APOO Antibody (Biotin)

Target: APOO (Apolipoprotein O (APOO))

Binding Specificity: AA 26-198

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOO antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human MICOS complex subunit MIC26 protein (26-198AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APOO

Target: APOO (Apolipoprotein O (APOO))

Alternative Name: APOO (APOO Products)

Synonyms: fam121b antibody, fp74f12 antibody, wu:fp74f12 antibody, zgc:123314 antibody, my025 antibody, FAM121B antibody, 0610008C08Rik antibody, 1110019O03Rik antibody, RGD1565289 antibody, MGC79016 antibody, si:rp71-1f1.3 antibody, wu:fr42a11 antibody, zgc:103766 antibody, apolipoprotein O, a antibody, apolipoprotein O antibody, apolipoprotein O L homeolog antibody, apolipoprotein O, b antibody, apooa antibody, apoo antibody, APOO antibody, Apoo antibody, apoo.L antibody, apoob antibody

Background:

Background: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).

Aliases: 0610008C08Rik antibody, 1110019O03Rik antibody, Apolipoprotein O antibody, APOO antibody, APOO_HUMAN antibody, FAM121B antibody, Family with sequence similarity 121B antibody, MGC130105 antibody, MGC130106 antibody, MGC4825 antibody, My025 antibody, MYO25 antibody, OTTHUMP00000023073 antibody, Protein FAM121B antibody, RP23-272D10.2 antibody

UniProt: Q9BUR5