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MBD3 antibody (AA 79-209)

MBD3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7159613
  • Target See all MBD3 Antibodies
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Binding Specificity
    • 14
    • 10
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 79-209
    Reactivity
    • 69
    • 29
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 9
    • 2
    Rabbit
    Clonality
    • 55
    • 14
    Polyclonal
    Conjugate
    • 41
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MBD3 antibody is un-conjugated
    Application
    • 45
    • 28
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human, Mouse
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
    Alternative Name
    MBD3 (MBD3 Products)
    Synonyms
    xmbd3 antibody, MGC69548 antibody, MBD3 antibody, DKFZp459N1635 antibody, AI181826 antibody, AU019209 antibody, methyl-CpG binding domain protein 3 S homeolog antibody, methyl-CpG binding domain protein 3 antibody, mbd3.S antibody, mbd3 antibody, MBD3 antibody, Mbd3 antibody
    Background

    Background: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.

    Aliases: AI181826 antibody, AU019209 antibody, MBD 3 antibody, Mbd3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding domain protein 3 antibody, Methyl CpG binding protein MBD3 antibody, Methyl-CpG-binding domain protein 3 antibody, Methyl-CpG-binding protein MBD3 antibody

    UniProt
    O95983
    Pathways
    Chromatin Binding
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