METAP2 antibody (AA 313-449)

Catalog No. ABIN7159581

Product Details anti-METAP2 Antibody

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Binding Specificity: AA 313-449

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METAP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Methionine aminopeptidase 2 protein (313-449AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for METAP2

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Alternative Name: METAP2 (METAP2 Products)

Synonyms: metap2 antibody, MGC53792 antibody, METAP2 antibody, GB13458 antibody, DDBDRAFT_0190923 antibody, DDBDRAFT_0304991 antibody, DDB_0190923 antibody, DDB_0304991 antibody, 4930584B20Rik antibody, A930035J23Rik antibody, AI047573 antibody, AL024412 antibody, AU014659 antibody, Amp2 antibody, Mnpep antibody, p67 antibody, p67eIF2 antibody, MAP2 antibody, MNPEP antibody, wu:fb98h06 antibody, zgc:66250 antibody, methionyl aminopeptidase 2 L homeolog antibody, methionyl aminopeptidase 2 antibody, methionine aminopeptidase 2 antibody, methionine aminopeptidase antibody, methionyl aminopeptidase 2 S homeolog antibody, methionyl aminopeptidase 2b antibody, metap2.L antibody, METAP2 antibody, metap2 antibody, LOC551771 antibody, CAALFM_C604080WA antibody, Metap2 antibody, metap2.S antibody, metap2b antibody

Background:

Background: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.

Aliases: A930035J23Rik antibody, AI047573 antibody, AL024412 antibody, Amp2 antibody, AU014659, antibody, EIF 2 associated p67 homolog antibody, EIF-2-associated p67 antibody, Initiation factor 2 associated 67 kDa glycoprotein antibody, Initiation factor 2-associated 67 kDa glycoprotein antibody, MAP 2 antibody, MAP2 antibody, MAP2_HUMAN antibody, MetAP 2 antibody, Metap2 antibody, Methionine aminopeptidase 2 antibody, Methionyl aminopeptidase 2 antibody, MGC102452 antibody, MGC127390 antibody, MGC53792 antibody, MNPEP antibody, p67 antibody, p67eIF2 antibody, Peptidase M antibody, Peptidase M2 antibody

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling