STEAP3 antibody (AA 1-207)

Catalog No. ABIN7159505

Product Details anti-STEAP3 Antibody

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Binding Specificity: AA 1-207

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STEAP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Metalloreductase STEAP3 protein (1-207AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Alternative Name: STEAP3 (STEAP3 Products)

Synonyms: STEAP3 antibody, 1010001D01Rik antibody, Tsap6 antibody, pHyde antibody, AHMIO2 antibody, STMP3 antibody, TSAP6 antibody, dudlin-2 antibody, STEAP3 metalloreductase antibody, STEAP family member 3 antibody, STEAP3 antibody, steap3 antibody, Steap3 antibody

Background:

Background: Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

Aliases: 1010001D01Rik antibody, Dudlin 2 antibody, Dudlin2 antibody, Dudulin 2 antibody, Dudulin-2 antibody, Dudulin2 antibody, h pH yde antibody, hTSAP6 antibody, Metalloreductase STEAP3 antibody, MGC93147 antibody, pH yde antibody, Six transmembrane epithelial antigen of prostate 3 antibody, Six transmembrane prostate protein 3 antibody, Six-transmembrane epithelial antigen of prostate 3 antibody, STEA 3 antibody, STEA3_HUMAN antibody, STEAP 3 antibody, STEAP family member 3 antibody, STEAP family member 3 metalloreductase antibody, STEAP3 antibody, STMP 3 antibody, STMP3 antibody, TSAP 6 antibody, TSAP6 antibody, Tumor suppressor activated pathway protein 6 antibody, Tumor suppressor pH yde antibody, Tumor suppressor-activated pathway protein 6 antibody

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis