Mesp2 antibody (AA 218-397)

Catalog No. ABIN7159423

Product Details anti-Mesp2 Antibody

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Binding Specificity: AA 218-397

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mesp2 antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Mesoderm posterior protein 2 protein (218-397AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Alternative Name: MESP2 (Mesp2 Products)

Synonyms: bHLHc6 antibody, SCDO2 antibody, mesoderm posterior 2 antibody, mesoderm posterior bHLH transcription factor 2 antibody, Mesp2 antibody, MESP2 antibody

Background:

Background: Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.

Aliases: Basic helix loop helix protein MESP 2 antibody, Basic helix loop helix protein MESP2 antibody, BHLH protein MesP2 antibody, bHLHc6 antibody, Class C basic helix-loop-helix protein 6 antibody, Hypothetical class II basic helix loop helix protein MESP 2 antibody, Hypothetical class II basic helix loop helix protein MESP2 antibody, Mesoderm posterior 2 antibody, mesoderm posterior 2 homolog (mouse) antibody, Mesoderm posterior 2 homolog antibody, Mesoderm posterior protein 2 antibody, Mesp 2 antibody, MESP2 antibody, MESP2_HUMAN antibody, SCDO 2 antibody, SCDO2 antibody

UniProt: Q0VG99