PKMYT1 antibody (AA 900-1101)
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- Target See all PKMYT1 Antibodies
- PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
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Binding Specificity
- AA 900-1101
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PKMYT1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase protein (900-1101AA)
- Isotype
- IgG
- Top Product
- Discover our top product PKMYT1 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
- Alternative Name
- PKMYT1 (PKMYT1 Products)
- Synonyms
- MYT1 antibody, 6230424P17 antibody, AW209059 antibody, Myt1 antibody, RGD1305434 antibody, myt1 antibody, protein kinase, membrane associated tyrosine/threonine 1 antibody, protein kinase, membrane associated tyrosine/threonine 1 S homeolog antibody, PKMYT1 antibody, pkmyt1 antibody, Pkmyt1 antibody, pkmyt1.S antibody
- Background
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Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on \'Thr-14\'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on \'Tyr-15\' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Aliases: cdc2 inhibitory kinase antibody, DKFZp547K1610 antibody, FLJ20093 antibody, Membrane associated tyrosine and threonine specific cdc2 inhibitory kinase antibody, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase antibody, MYT1 antibody, Myt1 kinase antibody, PKMYT 1 antibody, Pkmyt1 antibody, PMYT1_HUMAN antibody, PPP1R126 antibody, Protein kinase membrane associated tyrosine/threonine 1 antibody, Protein kinase Myt1 antibody, Protein phosphatase 1 regulatory subunit 126 antibody
- UniProt
- Q99640
- Pathways
- Mitotic G1-G1/S Phases, M Phase
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