MAGEC2 antibody (AA 1-150)

Catalog No. ABIN7159289

Product Details anti-MAGEC2 Antibody

Target: MAGEC2 (Melanoma Antigen Family C, 2 (MAGEC2))

Binding Specificity: AA 1-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEC2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Melanoma-associated antigen C2 protein (1-150AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAGEC2

Target: MAGEC2 (Melanoma Antigen Family C, 2 (MAGEC2))

Alternative Name: MAGEC2 (MAGEC2 Products)

Synonyms: CT10 antibody, HCA587 antibody, MAGEE1 antibody, MAGEC2 antibody, MAGE family member C2 antibody, melanoma antigen family C, 2 antibody, MAGEC2 antibody, Magec2 antibody

Background:

Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

Aliases: Cancer testis antigen 10 antibody, Cancer/testis antigen 10 antibody, CT10 antibody, HCA587 antibody, Hepatocellular cancer antigen 587 antibody, Hepatocellular carcinoma associated antigen 587 antibody, Hepatocellular carcinoma-associated antigen 587 antibody, MAGC2_HUMAN antibody, MAGE C2 antigen antibody, MAGE E1 antigen antibody, MAGE family member C2 antibody, MAGE-C2 antigen antibody, MAGE-E1 antigen antibody, MAGEC2 antibody, Melanoma antigen family C 2 antibody, Melanoma antigen family C2 antibody, Melanoma antigen family E 1 cancer/testis specific antibody, Melanoma associated antigen C2 antibody, Melanoma-associated antigen C2 antibody, MGC13377 antibody

UniProt: Q9UBF1