MAGEA3 antibody (AA 2-104)

Catalog No. ABIN7374180

Product Details anti-MAGEA3 Antibody

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Binding Specificity: AA 2-104

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Melanoma-associated antigen 3 protein (2-104AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAGEA3

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Alternative Name: MAGEA3 (MAGEA3 Products)

Synonyms: CT1.3 antibody, HIP8 antibody, HYPD antibody, MAGE3 antibody, MAGEA6 antibody, Mage-a3 antibody, MAGEA3 antibody, MAGE family member A3 antibody, melanoma antigen, family A, 3 antibody, melanoma antigen family A, 3 antibody, MAGEA3 antibody, Magea3 antibody

Background:

Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Aliases: Antigen MZ2 D antibody, Antigen MZ2-D antibody, Cancer/testis antigen 1.3 antibody, Cancer/testis antigen family 1 member 3 antibody, CT1.3 antibody, HIP8 antibody, HYPD antibody, MAGA3_HUMAN antibody, MAGE 3 antigen antibody, MAGE family member A3 antibody, MAGE-3 antigen antibody, MAGE3 antibody, MAGEA3 antibody, MAGEA6 antibody, Melanoma antigen family A 3 antibody, Melanoma associated antigen 3 antibody, Melanoma-associated antigen 3 antibody, MGC1461 antibody

UniProt: P43357