PRAME antibody (AA 1-509)
-
- Target See all PRAME Antibodies
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
-
Binding Specificity
- AA 1-509
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PRAME antibody is un-conjugated
-
Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Melanoma antigen preferentially expressed in tumors protein (1-509AA)
- Isotype
- IgG
- Top Product
- Discover our top product PRAME Primary Antibody
-
-
- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))
- Alternative Name
- PRAME (PRAME Products)
- Synonyms
- PRAME antibody, CT130 antibody, MAPE antibody, OIP-4 antibody, OIP4 antibody, 4930534P07Rik antibody, preferentially expressed antigen in melanoma antibody, PRAME antibody, Prame antibody
- Background
-
Background: Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
Aliases: 4930534P07Rik antibody, Cancer/testis antigen 130 antibody, CT130 antibody, MAPE antibody, Melanoma antigen preferentially expressed in tumors antibody, OIP 4 antibody, OIP-4 antibody, OIP4 antibody, OPA interacting protein 4 antibody, Opa interacting protein OIP4 antibody, OPA-interacting protein 4 antibody, PRAME antibody, PRAME_HUMAN antibody, Preferentially expressed antigen in melanoma antibody, Preferentially expressed antigen of melanoma antibody, RP23-250F8.3 antibody
- UniProt
- P78395
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding
-