MED23 antibody (AA 1014-1368) (Biotin)

Catalog No. ABIN7159129

Product Details anti-MED23 Antibody (Biotin)

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Binding Specificity: AA 1014-1368

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED23 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mediator of RNA polymerase II transcription subunit 23 protein (1014-1368AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MED23

Target: MED23 (Mediator Complex Subunit 23 (MED23))

Alternative Name: MED23 (MED23 Products)

Synonyms: CG3695 antibody, Dmel\\CG3695 antibody, Gal11/SUR2 antibody, Med23 antibody, Trap150 antibody, Trap150beta antibody, dSUR2 antibody, dTRAP150beta antibody, CRSP3 antibody, MED23 antibody, ARC130 antibody, CRSP130 antibody, CRSP133 antibody, DRIP130 antibody, MRT18 antibody, SUR-2 antibody, SUR2 antibody, 130kDa antibody, 3000002A17Rik antibody, Crsp3 antibody, ESTM7 antibody, Sur2 antibody, X83317 antibody, mKIAA1216 antibody, crsp3 antibody, si:ch211-272f15.2 antibody, zgc:91979 antibody, Mediator complex subunit 23 antibody, mediator complex subunit 23 antibody, mediator of RNA polymerase II transcription subunit 23 antibody, mediator complex subunit 23 L homeolog antibody, Mediator of RNA polymerase II transcription subunit 23 antibody, MED23 antibody, med23 antibody, LOC412332 antibody, Med23 antibody, med23.L antibody, sur-2 antibody

Background:

Background: Required for transcriptional activation subsequent to the assembly of the pre-initiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.

Aliases: 130 kDa transcriptional co activator antibody, 133 kDa transcriptional co activator antibody, Activator recruited cofactor 130 kDa component antibody, Activator-recruited cofactor 130 kDa component antibody, ARC 130 antibody, ARC130 antibody, Cofactor required for Sp1 transcriptional activation subunit 3 130 kDa antibody, Cofactor required for Sp1 transcriptional activation subunit 3 130 kDa mediator antibody, Cofactor required for Sp1 transcriptional activation subunit 3 antibody, CRSP 130 antibody, CRSP 130 kD subunit antibody, CRSP 133 antibody, CRSP 3 antibody, CRSP complex subunit 3 antibody, CRSP130 antibody, CRSP133 antibody, CRSP3 antibody, CRSP3 protein antibody, DKFZp434H0117 antibody, DRIP 130 antibody, DRIP130 antibody, hSur-2 antibody, KIAA1216 antibody, MED 23 antibody, med23 antibody, MED23_HUMAN antibody, Mediator complex subunit 23 antibody, Mediator of RNA polymerase II transcription subunit 23 antibody, MRT18 antibody, Protein sur-2 homolog antibody, SUR 2 antibody, SUR2 antibody, Transcriptional co activator CRSP 130 antibody, Transcriptional co activator CRSP130 antibody, Transcriptional coactivator CRSP130 antibody, Vitamin D3 receptor interacting protein antibody, Vitamin D3 receptor interacting protein complex 130 kDa component antibody, Vitamin D3 receptor-interacting protein complex 130 kDa component antibody

UniProt: Q9ULK4

Pathways: Regulation of Lipid Metabolism by PPARalpha