MED17 antibody (AA 411-651)

Catalog No. ABIN7159112

Product Details anti-MED17 Antibody

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Binding Specificity: AA 411-651

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mediator of RNA polymerase II transcription subunit 17 protein (411-651AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Alternative Name: MED17 (MED17 Products)

Synonyms: crsp6 antibody, CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, TRAP80 antibody, 77kDa antibody, C330002H14Rik antibody, Crsp6 antibody, Trap80 antibody, mediator of RNA polymerase II transcription subunit 17 antibody, mediator complex subunit 17 antibody, mediator complex subunit 17 L homeolog antibody, AOR_1_2446154 antibody, VDBG_01663 antibody, med17 antibody, med17.L antibody, MED17 antibody, Med17 antibody

Background:

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Aliases: 77-KD subunit antibody, Activator recruited cofactor 77 kDa component antibody, Activator-recruited cofactor 77 kDa component antibody, ARC77 antibody, Cofactor required for Sp1 transcriptional activation subunit 6 antibody, cofactor required for Sp1 transcriptional activation, subunit 6, 77 kDa antibody, CRSP complex subunit 6 antibody, CRSP6 antibody, CRSP77 antibody, DRIP80 antibody, med17 antibody, MED17_HUMAN antibody, Mediator complex subunit 17 antibody, Mediator of RNA polymerase II transcription subunit 17 antibody, Mediator of RNA polymerase II transcription subunit 17, S cerevisiae, homolog of antibody, Thyroid hormone receptor-associated protein complex 80 kDa component antibody, Thyroid hormone receptor-associated protein, 80-KD subunit antibody, Transcriptional coactivator CRSP77 antibody, Trap80 antibody, VITAMIN D RECEPTOR-INTERACTING PROTEIN, 80-KD antibody, Vitamin D3 receptor-interacting protein complex 80 kDa component antibody

UniProt: Q9NVC6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha