MED12 antibody (AA 1742-2011)
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- Target See all MED12 Antibodies
- MED12 (Mediator Complex Subunit 12 (MED12))
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Binding Specificity
- AA 1742-2011
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MED12 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Mediator of RNA polymerase II transcription subunit 12 protein (1742-2011AA)
- Isotype
- IgG
- Top Product
- Discover our top product MED12 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MED12 (Mediator Complex Subunit 12 (MED12))
- Alternative Name
- MED12 (MED12 Products)
- Synonyms
- ARC240 antibody, CAGH45 antibody, FGS1 antibody, HOPA antibody, MED12S antibody, OHDOX antibody, OKS antibody, OPA1 antibody, TNRC11 antibody, TRAP230 antibody, 230kDa antibody, Mopa antibody, OPA-1 antibody, Tnrc11 antibody, Trap230 antibody, mediator complex subunit 12 antibody, MED12 antibody, Med12 antibody, med12 antibody
- Background
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Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
Aliases: Activator recruited cofactor 240 kDa component antibody, Activator-recruited cofactor 240 kDa component antibody, ARC240 antibody, CAG repeat protein 45 antibody, CAGH45 antibody, HOPA antibody, KIAA0192 antibody, MED12 antibody, MED12_HUMAN antibody, Mediator complex subunit 12 antibody, Mediator of RNA polymerase II transcription subunit 12 antibody, OPA containing protein antibody, OPA-containing protein antibody, Thyroid hormone receptor associated protein complex 230 kDa component antibody, Thyroid hormone receptor-associated protein complex 230 kDa component antibody, TNRC11 antibody, Trap230 antibody, Trinucleotide repeat containing gene 11 protein antibody, Trinucleotide repeat-containing gene 11 protein antibody
- UniProt
- Q93074
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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