MASP2 antibody (AA 189-314) (HRP)

Catalog No. ABIN7158977

Product Details anti-MASP2 Antibody (HRP)

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Binding Specificity: AA 189-314

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MASP2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Mannan-binding lectin serine protease 2 protein (189-314AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MASP2

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Alternative Name: MASP2 (MASP2 Products)

Synonyms: MAP19 antibody, MASP-2 antibody, MASP1P1 antibody, sMAP antibody, MAp19 antibody, mannan binding lectin serine peptidase 2 antibody, mannan-binding lectin serine peptidase 2 antibody, MASP2 antibody, Masp2 antibody

Background:

Background: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.

Aliases: MASP2Mannan-binding lectin serine protease 2 antibody, EC 3.4.21.104 antibody, MBL-associated serine protease 2 antibody, Mannose-binding protein-associated serine protease 2 antibody, MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain, Mannan-binding lectin serine protease 2 B chain] antibody

UniProt: O00187

Pathways: Complement System