MLYCD antibody (AA 40-493)

Catalog No. ABIN7158953

Product Details anti-MLYCD Antibody

Target: MLYCD (Malonyl CoA Decarboxylase (MLYCD))

Binding Specificity: AA 40-493

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLYCD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Malonyl-CoA decarboxylase, mitochondrial protein (40-493AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MLYCD

Target: MLYCD (Malonyl CoA Decarboxylase (MLYCD))

Alternative Name: MLYCD (MLYCD Products)

Synonyms: MCD antibody, AI324784 antibody, Mcd antibody, MaLonyl CoA Decarboxylase antibody, malonyl-CoA decarboxylase antibody, mlcd-1 antibody, MLYCD antibody, Mlycd antibody

Background:

Background: Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids. Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling. May play a role in controlling the extent of ischemic injury by promoting glucose oxidation.

Aliases: DCMC_HUMAN antibody, hMCD antibody, Malonyl CoA decarboxylase antibody, Malonyl CoA decarboxylase mitochondrial antibody, Malonyl coenzyme A decarboxylase antibody, Malonyl-CoA decarboxylase antibody, MCD antibody, MGC59795 antibody, mitochondrial antibody, Mlycd antibody

UniProt: O95822

Pathways: Regulation of Carbohydrate Metabolic Process