DCP2 antibody (AA 1-385)

Catalog No. ABIN7158862

Product Details anti-DCP2 Antibody

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Binding Specificity: AA 1-385

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCP2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human m7GpppN-mRNA hydrolase protein (1-385AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DCP2

Target: DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))

Alternative Name: DCP2 (DCP2 Products)

Synonyms: DDBDRAFT_0185453 antibody, DDBDRAFT_0252811 antibody, DDB_0185453 antibody, DDB_0252811 antibody, 2410015D23Rik antibody, 5730537H01Rik antibody, AL118268 antibody, NUDT20 antibody, RGD1562909 antibody, mRNA-decapping enzyme 2 antibody, hypothetical protein antibody, decapping mRNA 2 antibody, CpipJ_CPIJ019463 antibody, PTRG_05936 antibody, dcp2 antibody, MCYG_05106 antibody, MGYG_07617 antibody, PGTG_03310 antibody, Tsp_04018 antibody, DCP2 antibody, Dcp2 antibody

Background:

Background: Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5\\\'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.

Aliases: DCP2 antibody, DCP2 decapping enzyme homolog (S. cerevisiae) antibody, DCP2, S. cerevisiae, homolog of antibody, DCP2_HUMAN antibody, decapping enzyme 2, S. cerevisiae, homolog of antibody, decapping enzyme homolog (S. cerevisiae) antibody, FLJ33245 antibody, hDpc antibody, m7GpppN-mRNA hydrolase antibody, mRNA decapping enzyme 2 antibody, mRNA-decapping enzyme 2 antibody, Nucleoside diphosphate-linked moiety X motif 20 antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 20 antibody, Nudix motif 20 antibody, NUDT20 antibody

UniProt: Q8IU60