KDM1B antibody (AA 451-544) (Biotin)

Catalog No. ABIN7158729

Product Details anti-KDM1B Antibody (Biotin)

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Binding Specificity: AA 451-544

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM1B antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific histone demethylase 1B protein (451-544AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KDM1B

Target: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Alternative Name: KDM1B (KDM1B Products)

Synonyms: AOF1 antibody, C6orf193 antibody, LSD2 antibody, bA204B7.3 antibody, dJ298J15.2 antibody, 4632428N09Rik antibody, AI482520 antibody, Aof1 antibody, lysine demethylase 1B antibody, lysine-specific histone demethylase 1B antibody, lysine (K)-specific demethylase 1B antibody, KDM1B antibody, LOC577549 antibody, kdm1b antibody, Kdm1b antibody

Background:

Background: Histone demethylase that demethylates \'Lys-4\' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated \'Lys-4\' of histone H3. Has no effect on tri-methylated \'Lys-4\', mono-, di- or tri-methylated \'Lys-9\', mono-, di- or tri-methylated \'Lys-27\', mono-, di- or tri-methylated \'Lys-36\' of histone H3, or on mono-, di- or tri-methylated \'Lys-20\' of histone H4 (By similarity).

Aliases: amine oxidase (flavin containing) domain 1 antibody, amine oxidase, flavin containing 1 antibody, AOF1 antibody, bA204B7.3 antibody, C6orf193 antibody, dJ298J15.2 antibody, Flavin-containing amine oxidase domain-containing protein 1 antibody, FLJ33898 antibody, FLJ34109 antibody, FLJ43328 antibody, KDM1B antibody, KDM1B_HUMAN antibody, LSD2 antibody, lysine (K)-specific demethylase 1B antibody, Lysine-specific demethylase 2 antibody, Lysine-specific histone demethylase 1B antibody, Lysine-specific histone demethylase 2 antibody

UniProt: Q8NB78

Pathways: Warburg Effect