KDM4A antibody (AA 127-364)

Catalog No. ABIN7158695

Product Details anti-KDM4A Antibody

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Binding Specificity: AA 127-364

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific demethylase 4A protein (127-364AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KDM4A

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Alternative Name: KDM4A (KDM4A Products)

Background:

Background: Histone demethylase that specifically demethylates \'Lys-9\' and \'Lys-36\' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 \'Lys-4\', H3 \'Lys-27\' nor H4 \'Lys-20\'. Demethylates trimethylated H3 \'Lys-9\' and H3 \'Lys-36\' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.

Aliases: JHDM3A antibody, JmjC domain containing histone demethylation protein 3A antibody, JmjC domain-containing histone demethylation protein 3A antibody, JMJD2 antibody, JMJD2A antibody, jumonji C domain containing histone demethylase 3A antibody, Jumonji domain containing 2 antibody, Jumonji domain containing 2A antibody, Jumonji domain containing protein 2A antibody, Jumonji domain-containing protein 2A antibody, KDM4A antibody, KDM4A_HUMAN antibody, KIAA0677 antibody, Lysine (K) specific demethylase 4A antibody, Lysine-specific demethylase 4A antibody, TDRD14A antibody, Tudor domain containing 14A antibody

UniProt: O75164

Pathways: Warburg Effect