KDM2B antibody (AA 1274-1336) (Biotin)

Catalog No. ABIN7158692

Product Details anti-KDM2B Antibody (Biotin)

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Binding Specificity: AA 1274-1336

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM2B antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lysine-specific demethylase 2B protein (1274-1336AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KDM2B

Target: KDM2B (Lysine (K)-Specific Demethylase 2B (KDM2B))

Alternative Name: KDM2B (KDM2B Products)

Synonyms: CXXC2 antibody, FBXL10 antibody, Fbl10 antibody, JHDM1B antibody, PCCX2 antibody, fbxl10 antibody, wu:fd13a09 antibody, zgc:85787 antibody, KDM2B antibody, Fbxl10 antibody, Cxxc2 antibody, E430001G17 antibody, Jhdm1b antibody, mKIAA3014 antibody, jhdm1b antibody, F6P23.18 antibody, F6P23_18 antibody, lysine demethylase 2B antibody, lysine (K)-specific demethylase 2Ba antibody, microRNA 7107 antibody, lysine (K)-specific demethylase 2B antibody, lysine (K)-specific demethylase 2B L homeolog antibody, F-box/RNI-like superfamily protein antibody, KDM2B antibody, kdm2ba antibody, Kdm2b antibody, MIR7107 antibody, kdm2b.L antibody, AT2G17020 antibody

Background:

Background: Histone demethylase that demethylates \'Lys-4\' and \'Lys-36\' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 \'Lys-4\' and dimethylated H3 \'Lys-36\' residue while it has weak or no activity for mono- and tri-methylated H3 \'Lys-36\'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Aliases: [Histone-H3]-lysine-36 demethylase 1B antibody, CXXC-type zinc finger protein 2 antibody, CXXC2 antibody, F box and leucine rich repeat protein 10 antibody, F box protein FBL10 antibody, F-box and leucine-rich repeat protein 10 antibody, F-box protein FBL10 antibody, F-box/LRR-repeat protein 10 antibody, Fbl10 antibody, FBXL10 antibody, JEMMA (Jumonji domain EMSY interactor methyltransferase motif) protein antibody, JHDM1B antibody, JmjC domain-containing histone demethylation protein 1B antibody, Jumonji C domain containing histone demethylase 1B antibody, Jumonji domain-containing EMSY-interactor methyltransferase motif protein antibody, kdm2b antibody, KDM2B_HUMAN antibody, Lysine (K) specific demethylase 2B antibody, Lysine-specific demethylase 2B antibody, PCCX2 antibody, Protein containing CXXC domain 2 antibody, Protein JEMMA antibody, Protein-containing CXXC domain 2 antibody

UniProt: Q8NHM5

Pathways: Tube Formation, Warburg Effect