SLC27A1 antibody (AA 453-570) (Biotin)

Catalog No. ABIN7158493

Product Details anti-SLC27A1 Antibody (Biotin)

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Binding Specificity: AA 453-570

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC27A1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Long-chain fatty acid transport protein 1 protein (453-570AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SLC27A1

Target: SLC27A1 (FATP1) (Fatty Acid Transport Protein 1 (FATP1))

Alternative Name: SLC27A1 (FATP1 Products)

Synonyms: ACSVL5 antibody, FATP antibody, FATP1 antibody, Fatp antibody, FATP-1 antibody, FATP-1c antibody, solute carrier family 27 member 1 antibody, solute carrier family 27 (fatty acid transporter), member 1 antibody, SLC27A1 antibody, Slc27a1 antibody

Background:

Background: Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity).

Aliases: SLC27A1 antibody, ACSVL5 antibody, FATP1Long-chain fatty acid transport protein 1 antibody, FATP-1 antibody, Fatty acid transport protein 1 antibody, EC 6.2.1.- antibody, Solute carrier family 27 member 1 antibody

UniProt: Q6PCB7

Pathways: Inositol Metabolic Process, Regulation of Lipid Metabolism by PPARalpha