CD43 antibody (AA 276-400)

Catalog No. ABIN7158299

Product Details anti-CD43 Antibody

Target: CD43 (SPN) (Sialophorin (SPN))

Binding Specificity: AA 276-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD43 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Leukosialin protein (276-400AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD43

Target: CD43 (SPN) (Sialophorin (SPN))

Alternative Name: SPN (SPN Products)

Synonyms: CD43 antibody, GALGP antibody, GPL115 antibody, LSN antibody, A630014B01Rik antibody, Cd43 antibody, Galgp antibody, Ly-48 antibody, Ly48 antibody, Lsn antibody, Lsn1 antibody, gpL115 antibody, sialophorin antibody, SPN antibody, Spn antibody

Background:

Background: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response .

Aliases: CD 43 antibody, CD43 antibody, CD43 antigen antibody, Galactoglycoprotein antibody, GALGP antibody, GPL 115 antibody, GPL115 antibody, Human gene for sialophorin antibody, Leucocyte sialoglycoprotein antibody, LEUK_HUMAN antibody, Leukocyte large sialoglycoprotein antibody, Leukocyte sialoglycoprotein antibody, Leukosialin antibody, LSN antibody, Ly-48 antibody, sialophorin (gpL115, leukosialin, CD43) antibody, Sialophorin antibody, Spn antibody

UniProt: P16150

Pathways: Regulation of Leukocyte Mediated Immunity