CD47 antibody (AA 44-141)

Catalog No. ABIN7158282

Product Details anti-CD47 Antibody

Target: CD47

Binding Specificity: AA 44-141

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD47 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Leukocyte surface antigen CD47 protein (44-141AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CD47

Target: CD47

Alternative Name: CD47 (CD47 Products)

Synonyms: IAP antibody, MER6 antibody, OA3 antibody, 9130415E20Rik antibody, AA407862 antibody, AI848868 antibody, AW108519 antibody, B430305P08Rik antibody, Itgp antibody, CD47/IAP antibody, alkaline phosphatase, intestinal antibody, CD47 molecule antibody, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody, Cd47 molecule antibody, ALPI antibody, CD47 antibody, Cd47 antibody

Background:

Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Aliases: Antigen identified by monoclonal antibody 1D8 antibody, Antigenic surface determinant protein OA3 antibody, CD 47 antibody, CD47 antibody, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody, CD47 antigen antibody, CD47 glycoprotein antibody, CD47 Molecule antibody, CD47_HUMAN antibody, IAP antibody, Integrin Associated Protein antibody, Integrin associated signal transducer antibody, Integrin-associated protein antibody, Leukocyte surface antigen CD47 antibody, MER 6 antibody, MER6 antibody, OA 3 antibody, OA3 antibody, OTTHUMP00000041152 antibody, OTTHUMP00000041153 antibody, Protein MER6 antibody, Rh related antigen antibody, Surface antigen identified by monoclonal antibody 1D8 antibody

UniProt: Q08722