LILRB3 antibody (AA 470-624) (Biotin)

Catalog No. ABIN7158273

Product Details anti-LILRB3 Antibody (Biotin)

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Binding Specificity: AA 470-624

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LILRB3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 3 protein (470-624AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Alternative Name: LILRB3 (LILRB3 Products)

Synonyms: CD85A antibody, HL9 antibody, ILT-5 antibody, ILT5 antibody, LILRA6 antibody, LIR-3 antibody, LIR3 antibody, PIRB antibody, Gp91 antibody, Lilrb3 antibody, PIR-B antibody, Pirb antibody, NILR-1 antibody, LILRB3 antibody, leukocyte immunoglobulin like receptor B3 antibody, paired Ig-like receptor B antibody, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 antibody, LILRB3 antibody, Pirb antibody

Background:

Background: May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).

Aliases: LILRB3 antibody, ILT5 antibody, LIR3 antibody, Leukocyte immunoglobulin-like receptor subfamily B member 3 antibody, LIR-3 antibody, Leukocyte immunoglobulin-like receptor 3 antibody, CD85 antigen-like family member A antibody, Immunoglobulin-like transcript 5 antibody, ILT-5 antibody, Monocyte inhibitory receptor HL9 antibody, CD antigen CD85a antibody

UniProt: O75022