SHoc2/Sur8 antibody (AA 3-89)

Catalog No. ABIN7158098

Product Details anti-SHoc2/Sur8 Antibody

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Binding Specificity: AA 3-89

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHoc2/Sur8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Leucine-rich repeat protein SHOC-2 protein (3-89AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SHoc2/Sur8

Target: SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))

Alternative Name: SHOC2 (SHOC2 Products)

Synonyms: AU017287 antibody, Sur8 antibody, mKIAA0862 antibody, SIAA0862 antibody, SOC2 antibody, SUR8 antibody, si:ch211-159c12.3 antibody, si:ch211-197i12.3 antibody, zgc:152956 antibody, soc-2 (suppressor of clear) homolog (C. elegans) antibody, SHOC2 leucine-rich repeat scaffold protein antibody, SHOC2 leucine-rich repeat scaffold protein S homeolog antibody, SHOC2, leucine rich repeat scaffold protein antibody, Shoc2 antibody, shoc2.S antibody, SHOC2 antibody, shoc2 antibody

Background:

Background: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the \\\'Ser-259\\\' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

Aliases: KIAA0862 antibody, Leucine-rich repeat protein SHOC-2 antibody, Protein soc-2 homolog antibody, Protein Sur-8 homolog antibody, Ras-binding protein Sur-8 antibody, SHOC2 antibody, SHOC2_HUMAN antibody

UniProt: Q9UQ13