LGI1 antibody (AA 35-285)

Catalog No. ABIN7158044

Product Details anti-LGI1 Antibody

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Binding Specificity: AA 35-285

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGI1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Leucine-rich glioma-inactivated protein 1 protein (35-285AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LGI1

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Alternative Name: LGI1 (LGI1 Products)

Synonyms: ADLTE antibody, ADPAEF antibody, ADPEAF antibody, EPITEMPIN antibody, EPT antibody, ETL1 antibody, IB1099 antibody, BB130740 antibody, MGC146600 antibody, LGIa antibody, fb78h12 antibody, wu:fb78h12 antibody, zgc:65886 antibody, leucine rich glioma inactivated 1 antibody, leucine-rich repeat LGI family, member 1 antibody, leucine-rich, glioma inactivated 1 antibody, leucine-rich, glioma inactivated 1b antibody, leucine-rich, glioma inactivated 1a antibody, LGI1 antibody, Lgi1 antibody, lgi1 antibody, lgi1b antibody, lgi1a antibody

Background:

Background: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

Aliases: ADLTE antibody, ADPAEF antibody, ADPEAF antibody, Epitempin 1 antibody, EPITEMPIN antibody, Epitempin-1 antibody, EPT antibody, ETL1 antibody, IB1099 antibody, leucine rich glioma inactivated 1 antibody, Leucine rich glioma-inactivated protein 1 antibody, Leucine-rich glioma-inactivated protein 1 antibody, LGI1 antibody, LGI1_HUMAN antibody, OTTHUMP00000020121 antibody, OTTHUMP00000020122 antibody

UniProt: O95970