Laminin beta 1 antibody (AA 523-661)

Catalog No. ABIN7157878

Product Details anti-Laminin beta 1 Antibody

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Binding Specificity: AA 523-661

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Laminin beta 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Laminin subunit beta-1 protein (523-661AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Laminin beta 1

Target: Laminin beta 1 (LAMB1) (Laminin, beta 1 (LAMB1))

Alternative Name: LAMB1 (LAMB1 Products)

Synonyms: CLM antibody, LIS5 antibody, fc20b05 antibody, gup antibody, lamb1 antibody, sb:cb95 antibody, wu:fc20b05 antibody, Lamb1-1 antibody, LAMB1 antibody, C77966 antibody, C80098 antibody, C81607 antibody, D130003D08Rik antibody, Lamb-1 antibody, laminin subunit beta 1 antibody, laminin, beta 1a antibody, laminin B1 antibody, LAMB1 antibody, lamb1a antibody, Lamb1 antibody, lamb1 antibody

Background:

Background: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.

Aliases: CLM antibody, Cutis laxa with marfanoid phenotype antibody, LAM B1 antibody, LAMB 1 antibody, LAMB1 antibody, LAMB1_HUMAN antibody, Laminin B1 antibody, Laminin B1 chain antibody, Laminin beta 1 chain antibody, Laminin beta 1 chain precursor antibody, Laminin beta1 antibody, Laminin subunit beta 1 antibody, Laminin subunit beta-1 antibody, Laminin-1 subunit beta antibody, Laminin-10 subunit beta antibody, Laminin-12 subunit beta antibody, Laminin-2 subunit beta antibody, Laminin-6 subunit beta antibody, Laminin-8 subunit beta antibody, LIS5 antibody, MGC142015 antibody

UniProt: P07942