B3GNT5 antibody (AA 65-344)

Catalog No. ABIN7157832

Product Details anti-B3GNT5 Antibody

Target: B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 5 (B3GNT5))

Binding Specificity: AA 65-344

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B3GNT5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase protein (65-344AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for B3GNT5

Target: B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 5 (B3GNT5))

Alternative Name: B3GNT5 (B3GNT5 Products)

Synonyms: B3GN-T5 antibody, beta3Gn-T5 antibody, beta3GnT5 antibody, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 antibody, B3GNT5 antibody, B3gnt5 antibody

Background:

Background: Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc4Cer, paragloboside), resulting in the synthesis of Lc3Cer and neolactopentaosylceramide (nLc5Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Aliases: B3GNT5Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase antibody, EC 2.4.1.206 antibody, Lactotriaosylceramide synthase antibody, Lc(3)Cer synthase antibody, Lc3 synthase antibody, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5 antibody, BGnT-5 antibody, Beta-1,3-Gn-T5 antibody, Beta-1,3-N-acetylglucosaminyltransferase 5 antibody, Beta3Gn-T5 antibody

UniProt: Q9BYG0