KMO antibody (AA 1-486)

Catalog No. ABIN7157756

Product Details anti-KMO Antibody

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Binding Specificity: AA 1-486

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KMO antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Kynurenine 3-monooxygenase protein (1-486AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KMO

Target: KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))

Alternative Name: KMO (KMO Products)

Synonyms: AI046660 antibody, dJ317G22.1 antibody, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) antibody, kynurenine 3-monooxygenase antibody, Kmo antibody, KMO antibody

Background:

Background: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Aliases: dJ317G22.1 antibody, kmo antibody, KMO_HUMAN antibody, Kynurenine 3 hydroxylase antibody, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase) antibody, Kynurenine 3 monooxygenase antibody, Kynurenine 3-hydroxylase antibody, Kynurenine 3-monooxygenase antibody, RP1-317G22.1 antibody

UniProt: O15229