NUF2 antibody (AA 165-464)

Catalog No. ABIN7157665

Product Details anti-NUF2 Antibody

Target: NUF2 (NUF2, NDC80 Kinetochore Complex Component (NUF2))

Binding Specificity: AA 165-464

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Kinetochore protein Nuf2 protein (165-464AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for NUF2

Target: NUF2 (NUF2, NDC80 Kinetochore Complex Component (NUF2))

Alternative Name: NUF2 (NUF2 Products)

Synonyms: 2410003C07Rik antibody, AU044112 antibody, C85691 antibody, Cdca1 antibody, NUF2R antibody, CDCA1 antibody, CT106 antibody, zgc:56708 antibody, cdca1 antibody, ct106 antibody, nuf2 antibody, nuf2-a antibody, nuf2-b antibody, nuf2r antibody, xNuf2 antibody, cdca1-B antibody, xnuf2 antibody, NUF2, NDC80 kinetochore complex component antibody, NUF2, NDC80 kinetochore complex component, homolog antibody, spindle pole body protein Nuf2 antibody, NUF2, NDC80 kinetochore complex component L homeolog antibody, NUF2, NDC80 kinetochore complex component S homeolog antibody, Nuf2 antibody, NUF2 antibody, nuf2 antibody, nuf2.L antibody, nuf2.S antibody

Background:

Background: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).

Aliases: Cancer/testis antigen 106 antibody, CDCA 1 antibody, CDCA1 antibody, Cell division cycle associated 1 antibody, Cell division cycle associated protein 1 antibody, Cell division cycle-associated protein 1 antibody, CT106 antibody, hNuf 2 antibody, hNuf2 antibody, hNuf2R antibody, hsNuf2 antibody, Kinetochore protein Nuf2 antibody, Nuf 2 antibody, NUF2 antibody, NUF2 NDC80 kinetochore complex component antibody, NUF2 NDC80 kinetochore complex component homolog antibody, NUF2, S. cerevisiae, homolog of antibody, NUF2_HUMAN antibody, NUF2R antibody

UniProt: Q9BZD4

Pathways: Maintenance of Protein Location